Hold two weapons: Press Down to switch to your second weapon slot. This is useful if you are saving a rail rocket or shotgun. Also, press Up to switch between dynamite and splitter grenades if available.
Quick clear: While fighting a group of enigmas and there is a Dark Mark Evil Tree, quickly destroy the tree before fighting any enemies. When it is destroyed, it will shoot a shockwave, instantly destroying all enemies in that area.
Rapid fire pistol: Hold down the fire button R on the pistol Redeemer to fan it, or shoot in rapid fire.
Blood vision: Click the Right Analog-stick to activate your blood vision.
Defeating Banshees: Be careful while fighting banshees. If you cut off their arms and they still live, they will fire non-stop energy balls at you.
Defeating Lazaurus: While fighting Lazaurus for the final time, hide in the house when he is using his twister move; it will shield you. Also, when he shoots his fireballs and smoke clouds, shoot them; they will blow up and you will be unharmed.
Ducking: Click the Left Analog-stick to duck.
Evil deeds: Blood Frenzy: Adds a supernatural boost to hand-to-hand combat.
Black Shroud: Covers you in a black shroud of darkness that hurts enemies when they attack for a short time.
Immortal Friends: No matter how many times you shoot Cassidy or Tala, they will not die.
Soul Stealer: Sucks the souls right out of living enemies can be used at a distance.
Turn: Turns some enemies against each other for a short period of time.
Good deeds: Fear: Some enigmas will run scared for a short time.
Mystic Armor: Strong armor possible 0 damage for a short time.
Silver Bullet: Infinite and more powerful bullets for a short time.
Vindicator: Shoots a chain of lighting that instantly destroys most small monsters.